United States Treatment Centers

Henry Ford Hospital Department of Dermatology:

Iltefat H. Hamzavi, MD
Qing-Sheng Mi, MD, PhD
Li Zhou, MD
Richard Huggins, MD
Marsha Henderson, MD
Henry W. Lim, MD

Our research department conducts both clinical and basic science research in vitiligo. On the clinical side, our primary focus is on improving outcomes of vitiligo surgery, imaging lesions to understand the progression of vitiligo. We are also investigating new ways to use light therapy. The basic science research performed in our department studies focuses on the autoimmune mechanisms of vitiligo. This is where the body’s immune cells, which usually fight off infection, attack their own cells including melanocytes, which are pigment producing cells. We are currently looking at regulatory cells and certain cell markers to gain a better understanding of how the immune system acts in people with vitiligo. We regularly report our results to our local patient support group to ensure this is work they believe will help them improve their condition.

Address: Henry Ford New Center One, 3031 W. Grand Blvd, Detroit, MI, USA 48202

Website: https://www.henryford.com/services/skin/treatments/rare-conditions/vitiligo


University of Texas Southwestern Department of Dermatology:

Amit G. Pandya, MD

Our research center is focused on research to improve the classification, diagnosis, prognosis and treatment of vitiligo. We have developed a vitiligo specialty clinic at the University of Texas Southwestern Medical Center in Dallas, TX which has seen over 1000 patients since 2008. We have also created a robust vitiligo registry with over 250 patients thus far which includes a bio-bank of lesional skin and serum samples. All patients in this registry undergo an extensive history and physical exam to obtain data comprising 54 items and 20 pages of information per patient. We are collecting longitudinal data from these patients to examine changes in various outcomes over the course of disease, as well as before and after treatment. Biomarker studies are being performed with the serum samples and new findings regarding vitiligo pathogenesis and treatment have been made with data and biobank samples from this registry. In addition to the above research, we are conducting studies on patient quality of life, outcome measures, disease activity indices and patient satisfaction with treatment. Recently we described a new clinical sign of active vitiligo, known as “confetti-like depigmentation” (Sosa, et al. JAAD 2015) which can be helpful in identifying patients requiring aggressive therapy and for entry into studies on new therapeutic agents.

Address: University of Texas Southwestern Medical Center, 5939 Harry Hines Blvd #300, Dallas, TX, USA 75390

Website: www.utswmedicine.org/conditions-specialties/dermatology/pigmentary-disorders.html


The University of Massachusetts Medical School Department of Dermatology:

John Harris, MD, PhD

Our current research focuses on the mechanisms of autoimmunity in vitiligo and the development of new treatments using animal models that can then be applied to human patients. We are currently using basic, translational, and clinical research strategies to better understand vitiligo pathogenesis. In the lab, we focus on two aspects of vitiligo: First, we study how abnormal, “stressed” melanocytes alert the immune system to their presence. We believe that, once stressed, melanocytes produce signals that recruit T cells to the skin, which then find the melanocytes and kill them. Second, we study how the T cells detect these signals, enter the skin, find the melanocytes, and kill them. We use multiple approaches to address these questions, including analysis of skin, blood, and serum from vitiligo patients, culturing normal primary human melanocytes, as well as a mouse model of vitiligo that we developed, which closely resembles human disease.

Address: Vitiligo Clinic and Research Center - University of Massachusetts Medical School - Ambulatory Care Center, 55 Lake Ave N

Worcester, MA 01655

Website: www.umassmed.edu/vitiligo/

University of Arkansas Department of Dermatology:

Gisela Erf (U Arkansas) – Modeling vitiligo in the chicken

University of California San Francisco Department of Dermatology:

Maria Wei (UCSF) – Melanoma/melanocyte biology

University of California Irvine Department of Dermatology:

Anand Ganesan (UC Irvine) – Melanoma/melanocyte pigmentation

University of Colorado Department of Dermatology:

Richard Spritz (U Colorado) – Vitiligo genetics
Stanca Birlea (U Colorado) – Melanocyte regeneration in vitiligo
David Norris (U Colorado) – Melanocyte regeneration in vitiligo, melanoma, alopecia areata
Tamara Terzian (U Colorado) – Melanoma and vitiligo

New York University Department of Dermatology:

Prashiela Manga (NYU) – Chemical-induced vitiligo

Loyola University Department of Dermatology:

Caroline Le Poole (Loyola U) – Vitiligo immunology, HSP70i, chemical-induced vitiligo

The Vitiligo and Pigmentation Institute of Southern California:

Pearl E. Grimes, MD, FAAD

Address:  5670 Wilshire Blvd Suite 650, Los Angeles, CA 90036

Website: www.pearlgrimesmd.com/contact-pigmentation-specialist-los-angeles/

Phone: (323) 426-6311

University of Texas- Austin

Ammar M Ahmed, MD

Address: 313 E 12th St, Suite 103, Austin, TX 78701